The Story of CM8®

CM8® Developed at the National Institute of Health

For over 40 years of dedicated service to the US government, Dr. Harry Diehl worked for the prestigious , National Institutes of Health (NIH) in the Laboratory of Chemistry of the National Institute of Arthritis, Metabolic, and Digestive Diseases located in Bethesda, Maryland. In 1964, at the age of 40, Mr. Diehl became concernerned about a neighbor's pain and disability from rheumatoid arthritis. His condition deteriorated over time until he became disabled. The neighbor had a family to support, but his arthritis made that impossible. Diehl was a deeply religious man whose feelings overwhelmed him as his friend's condition worsened. Harry thought, "Here I am working for the US Government at the National Institutes of Health, and I have never seen anything that was good for curing arthritis." He decided to take the initiative to establish a laboratory in his home to immerse himself and embark on a search for something to relieve the pain and disability of his neighbor and the millions of people who suffer from arthritis.

As a researcher, Diehl knew that finding a cure for arthritis first meant inducing the disease experimentally in research animals. He started with mice, and quickly realized that he was unable to induce arthritis in them. Diehl said he tried every way he could to give those mice arthritis, but they just would not get it. Then, he contacted a fellow researcher in California who wrote to him, "If you or anyone else can give mice arthritis, I want to know about it, because mice are 100% immune to arthritis." At that moment, Diehl's research instincts told him that what he wanted was already somewhere in those mice.

CM8® Development Methodology

Utilizing thin layer chromatography of methylene chloride extract from macerated mice, Diehl noticed a mysterious compound. It was a long, tedious job, working on his own in his spare time, but Diehl finally found, isolated, and identified the extract. It was cetyl myristoleate - and it protected mice from arthritis. Now having isolated the compound, Mr. Diehl went about molecular recreation of it. This meant that rather than destroying mice to get a quantity of this amazing molecule, Harryhad learned to make it in the laboratory. Cetyl Myristoleate could be made synthetically by chemically combining cetyl alcohol, with myristollic acid and he found that this synthesized form of Cetyl Myristoleate was just as effective in providing rats immunity to adjuvant-induced arthritis as the naturally occurring form (extracted from mice).

To test his theory that mice are immune to arthritis because of cetyl myristoleate, Diehl began to experiment on laboratory rats. The next step was to use the substance to prevent arthritis in other animals. Harry injected it into two groups of rats that he knew developed arthritis when injected with Freund's adjuvant. He was pleased to find that the group of rats also injected with cetyl myristoleate remained arthritis-free, and grew an average of 5.7 times as much as the control group that was not given the cetyl myristoleate, and which had in fact developed arthritis. This research was reported in an article written in conjunction with one of his colleagues at NIH in the Journal of Pharmaceutical Sciences. In summary, this paper reports that ten normal mice were injected in the tail with arthritis-inducing Freund's Adjuvant (heat-killed desiccated Mycobacterium butyricum) to which rats and certain other rodents are susceptible.

CM8® Findings Proven & Published

Diehl’s research findings on cetyl myristoleate were published in the March 1994 issue of the American Journal of Pharmaceutical Sciences, the prestigious peer review journal of the American Pharmaceutical Association and the American Chemical Society (VOL 83, #3, March 1994, pages 296-299). Mr. Diehl subsequently received three U.S. Patents for “use” on cetyl myristoleate, the first in 1977 on cetyl myristoleate, the second in 1978 for the treatment of rheumatoid arthritis, and then in 1996 for the treatment on osteo-arthritis. After receiving his first “use” patent, Mr. Diehl immediately approached the pharmaceutical industry with his amazing discovery. Unfortunately, none of the pharmaceutical companies were interested in his discovery, probably because cetyl myristoleate was a natural substance and therefore could not be granted a “product” patent, which meant that there would not be any exclusivity and the drug firms couldn’t make billions of dollars. The chemical formula for cetyl myristoleate is (Z)-ROCO(CH2)7CH =CH(CH2)3CH3.Cetyl myristoleate was unrecorded in chemical literature until Diehl's discovery was reported. To this day, in an effort to obfuscate the proven effects of CM8®, the current Merck Index of Chemicals does not even "list" cetyl myristoleate.

Being a scientist and not a marketing person, Mr. Diehl knew of no other way to bring Cetyl Myristoleate to the public, and consequently his discovery sat on the shelf collecting dust until he, himself, started developing arthritis. As he grew older, he began to experience some osteoarthritis in his hands, knees, and the heels of his feet. His family physician tried the usual regimen of cortisone and non-steroidal anti-inflammatory drugs without much effect on the course of the disease. Finally his physician told Harry he could not have any more cortisone. "So," Diehl said, "I thought about my discovery, and I decided to make a batch and use it on myself. " He did, and his symptoms of osteo-arthritis disappeared. The rest, as they say, is history.

CM8® Results Recognized

Wikipedia: "Although not as well known as glucosamine and/or chondroitin, there is a growing awareness that cetyl myristoleate equals or surpasses them in the treatment of the body pains brought on by various maladies such as bursitis, gout, osteoarthritis, rheumatoid arthritis, fibromyalgia, and sports related injuries."

Answers.com: "Recent published reports offer anecdotal evidence that Cetyl Myristoleate may provide significant amelioration of various arthritic conditions."

Excerpts used with permission from:

www.harrydiehl.com
www.wikipedia.com
www.answers.com
www.cm8.com